Compile Data Set for Download or QSAR
Found 201 from Barrow Neurological Institute
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)copy SMILEScopy InChI
Affinity DataKi:  0.0120nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM86311(CAS_485-35-8 | Cytisine | Cytisine-(-) | NSC_22407...)copy SMILEScopy InChI
Affinity DataKi:  0.240nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50047021(2-(6-(2-hydroxy-2-phenylethyl)-1-methylpiperidin-2...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50004108((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...)copy SMILEScopy InChI
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM85207(CAS_123990 | NSC_123990 | Suberyldicholine)copy SMILEScopy InChI
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50061567(1,1-Dimethyl-4-phenyl-piperazin-1-ium | CHEMBL1347...)copy SMILEScopy InChI
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)copy SMILEScopy InChI
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM8959((2-Mercaptoethyl)trimethylammonium iodide acetate ...)copy SMILEScopy InChI
Affinity DataKi:  170nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM81458(CAS_57-94-3 | NSC_6000 | d-Tubocurarine)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM86309(CAS_21019-30-7 | Methyllycaconitine | NSC_5311278)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50061568(2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50026220(2-hydroxy-N,N,N-trimethylethanaminium | CHEMBL2824...)copy SMILEScopy InChI
Affinity DataKi:  7.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM86424(CAS_39764 | NSC_39764 | Vecuronium)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM86425(CAS_27350 | NSC_27350 | Pancuronium)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM10709(1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM50143313((12S,13aS)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by PDSP Ki Database
LigandPNGBDBM86423(Alcuronium | CAS_5311001 | NSC_5311001)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0S2VPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322518((+/-)2-(3,4-Dichlorophenyl)-3,5,5-trimethylmorphol...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322518((+/-)2-(3,4-Dichlorophenyl)-3,5,5-trimethylmorphol...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322517((2S,3S)-2-(3,5-Difluorophenyl)-3,5,5-trimethylmorp...)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322513((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...)copy SMILEScopy InChI
Affinity DataIC50: 204nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 241nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322523((2S,3S)-2-(4-Chlorophenyl)-3,5,5-trimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 285nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322514((2S,3S)-2-(Naphthalen-2-yl)-3,5,5-trimethylmorphol...)copy SMILEScopy InChI
Affinity DataIC50: 334nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322518((+/-)2-(3,4-Dichlorophenyl)-3,5,5-trimethylmorphol...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322515((2S,3S)-2-(Naphthalen-1-yl)-3,5,5-trimethylmorphol...)copy SMILEScopy InChI
Affinity DataIC50: 411nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322511((2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorp...)copy SMILEScopy InChI
Affinity DataIC50: 415nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322514((2S,3S)-2-(Naphthalen-2-yl)-3,5,5-trimethylmorphol...)copy SMILEScopy InChI
Affinity DataIC50: 453nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322510((2S,3S)-2-(4-Chlorophenyl)-3,4,5,5-tetramethylmorp...)copy SMILEScopy InChI
Affinity DataIC50: 527nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322530((2S,3S)-2-Phenyl-3,5,5-trimethylmorpholin-2-ol | C...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Antagonist activity at alpha4beta2 nicotinic receptor in human SH-EP1 cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322531((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322529((2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322519((2S,3S)-2-(3,4-Difluorophenyl)-3,5,5-trimethylmorp...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322523((2S,3S)-2-(4-Chlorophenyl)-3,5,5-trimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322522((2S,3S)-3,5,5-Trimethyl-2-(4-methylphenyl)morpholi...)copy SMILEScopy InChI
Affinity DataIC50: 832nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322517((2S,3S)-2-(3,5-Difluorophenyl)-3,5,5-trimethylmorp...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322530((2S,3S)-2-Phenyl-3,5,5-trimethylmorpholin-2-ol | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322527((2S,3S)-2-(m-Tolyl)-3,5,5-trimethylmorpholin-2-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322525((2S,3S)-2-(3-Nitrophenyl)-3,5,5-trimethylmorpholin...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322520((2S,3S)-2-Biphenyl-4-yl-3,5,5-trimethylmorpholin-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at alpha3beta4 nicotinic receptor in human SH-SY5Y cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322529((2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at alpha4beta2 nicotinic receptor in human SH-EP1 cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Barrow Neurological Institute

Curated by ChEMBL
LigandPNGBDBM50322529((2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholi...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q9NPubMed
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